An Integrative Database of β-Lactamase Enzymes: Sequences, Structures, Functions, and Phylogenetic Trees
نویسندگان
چکیده
منابع مشابه
Simulating sequences and phylogenetic trees
Using the seqgen() function available in the phyclust package [1], data were simulated by mutating DNA sequences along phylogenetic trees. The topology of the trees were generated at two stages via the ms program [1, 2]. At the first stage we randomly generated a root sequence and a star-like ancestor tree having equal branch lengths and tips equal to the number of desired clusters. The tip lab...
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The CATH database of protein structures contains approximately 18000 domains organized according to their (C)lass, (A)rchitecture, (T)opology and (H)omologous superfamily. Relationships between evolutionary related structures (homologues) within the database have been used to test the sensitivity of various sequence search methods in order to identify relatives in Genbank and other sequence dat...
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 2019
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.02319-18